Selected Publications
Front Mol Neurosci 11:104
April 04, 2018
Christina's first first-author research article. We describe a patient mutation in KDM5C which has altered gene regulatory function in neurons.
Mol Cell Neurosci 87:35-45
December 25, 2017
Review article by Bobby & Farris on alternative splicing in the brain.
Neuroscience 370:170-180
May 29, 2017
Bobby's first first-author research paper published.
Epigenomics 8(12):1689-1708
November 14, 2016
Tricia's first first-author paper published
Cell Rep. 14(5):1000-9.
February 09, 2016
Characterization of Kdm5c-Knockout mice. These mice will be valuable for future therapeutic development of intellectual disability and autism spectrum disorders.
Epigenomics. 7(3):503-19. Review Article.
March 01, 2015
Christina's first first-author paper. We summarized neuroveleopmental disorders associated with mutations in regulators of the most-extensively controlled histone modification, H3K4me.
Nat Commun. ;6:6002. doi: 10.1038/ncomms7002.
January 22, 2015
The first paper from the lab! We developped a new RNA-seq method which allows us to profile full-length transcripts.
Nat Struct Mol Biol. 18(7):769-76. doi: 10.1038/nsmb.2062.
June 22, 2011
We found that ADD domain of ATRX, which is enriched with ATRX-syndrome mutations, is a reading module for heterochromatin histone methylation status, low H3K4me and hight H3K9me3.
Cell. 128(6):1077-88. Epub 2007 Feb 22.
February 22, 2007
We discovered the first family of enzymes which can remove H3K4me3. One of the family members, JARID1C/KDM5C was known to be mutated in X-linked intellectual disability. We linked hitone methylation dynamics and human cognitive development for the first time.
